In Treatment of Pain due to muscle spasmZinase-MR Tablet is a combination medicine that contains a painkiller as well as a muscle relaxant. It is used to relieve pain, inflammation, and swelling in conditions that affect muscles. Also, it effectively relieves muscle stiffness or spasm, thereby improving muscle movement. It works by blocking chemical messengers in the brain that tell us we have pain.Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common Side Effects :
Abdominal pain
Constipation
Flatulence
Stomach inflammation
Diarrhea
Nausea
Vomiting
Mouth ulcer
Dizziness
Drowsiness
Headache
Palpitations
High blood pressure
Bronchospasm
Abnormal liver enzyme

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zinase-MR Tablet may be taken with or without food, but it is better to take it at a fixed time.

Zinase-MR Tablet is a combination of two medicines: Etoricoxib and Thiocolchicoside, which relieves pain and relaxes the muscles. Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Thiocolchicoside is a muscle relaxant. It works on the centers in the brain and spinal cord to relieve muscle stiffness or spasm and to improve pain and movement of muscles.

Alcohol:
It is unsafe to consume alcohol with Zinase-MR Tablet.

Pregnancy:
Zinase-MR Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breastfeeding:
Information regarding the use of Zinase-MR Tablet during breastfeeding is not available. Please consult your doctor.

Driving:
Zinase-MR Tablet may cause side effects which could affect your ability to drive.If you experience dizziness, vertigo or somnolence while on treatment with Zinase-MR Tablet, avoid driving.

Kidney:
Zinase-MR Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Zinase-MR Tablet may not be needed in these patients. Please consult your doctor.Use of Zinase-MR Tablet is not recommended in patients with severe kidney disease.

Liver:
Zinase-MR Tablet should be used with caution in patients with liver disease. Dose adjustment of Zinase-MR Tablet may be needed. Please consult your doctor.Use of Zinase-MR Tablet is not recommended in patients with severe liver disease.

Zinase-MR Tablet helps relieve pain due to muscle spasm.
It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Zinase-MR Tablet as it may cause excessive drowsiness. 
Regularly monitor your blood pressure while taking this medicine, particularly in the first two weeks after starting treatment.
Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.
Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.

If you miss a dose of Zinase-MR Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.