Trioderm-OC Cream is a combination medicine used in the treatment of skin infections. It works by killing microorganisms that cause infection. It also blocks the release of certain chemical messengers that cause redness, swelling, and itching. Trioderm-OC Cream is for external use only. You should use it in the dose and duration as advised by your doctor. This medicine should be used regularly to get the most benefit from it. Do not use more than you need as it will not clear your condition faster and some side effects may be increased. If your condition goes on for longer than four weeks or gets worse at any time, let your doctor know. The effects of medicine can be increased by keeping the affected area clean and dry, and washing hands before and after treating the infection.Some of the common side effects include skin peeling, skin irritation, redness or itching at the site of application. If the side effects bother you or do not go away, let your doctor know. Avoid direct contact with eyes, nose, or mouth. If accidental exposure occurs, rinse immediately with plenty of water.It is not likely that other medicines you take by mouth or injection will affect the way it works but talk to your doctor before using it if you have used a similar medicine before and had an allergic reaction. This medicine should only be used if it is clearly needed during pregnancy.