In Peripheral vascular diseasePeripheral vascular disease refers to the condition of disturbed blood circulation in blood vessels. Trental 400 Tablet PR prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). It helps prevent the formation of blood clots and also prevents the existing ones from growing bigger in size. Make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine.In Intermittent claudicationIntermittent claudication refers to muscle pain on mild exertion (ache, cramp, numbness or sense of fatigue), classically in the calf muscle, which occurs during exercise or even walking, and it gets better with a short period of rest. Trental 400 Tablet PR helps relieve this pain in the legs that is caused due to disturbed blood supply in the legs. It helps prevent formation of blood clots, improves blood flow and maintains free flowing of blood in your body.show moreshow less

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common Side Effects :
Bloating
Diarrhea
Flushing (sense of warmth in the face, ears, neck and trunk)
Headache
Heartburn
Lightheadedness
Nausea
Stomach discomfort
Vomiting
Weakness
Dizziness
Sleep disorder

Use it as advised by your doctor or check the label for directions before use. Trental 400 Tablet PR is to be taken with food.

Trental 400 Tablet PR is a peripheral vasodilator. It works by decreasing the thickness (viscosity) of blood, allowing it to pass more easily through the blood vessels. This effect is beneficial in peripheral vascular disease, where the blood vessels in the arms and legs are narrowed.

Alcohol:
It is not known whether it is safe to consume alcohol with Trental 400 Tablet PR. Please consult your doctor.

Pregnancy:
Trental 400 Tablet PR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breastfeeding:
Trental 400 Tablet PR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving:
Trental 400 Tablet PR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney:
Trental 400 Tablet PR should be used with caution in patients with kidney disease. Dose adjustment of Trental 400 Tablet PR may be needed. Please consult your doctor.

Liver:
There is limited information available on the use of Trental 400 Tablet PR in patients with liver disease. Please consult your doctor.

Take it as per dose and duration suggested by your doctor.
Do not drive or perform activities that require mental focus until you know how Trental 400 Tablet PR affects you.
Your doctor may get regular blood tests done to monitor liver function while taking this medicine. 
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Take it with food, preferably at the same time everyday to avoid missing a dose.

If you miss a dose of Trental 400 Tablet PR, skip it and continue with your normal schedule. Do not double the dose.