Pio Rectal Ointment is a medicine used in the treatment of anal fissures and hemorrhoids (piles). It helps in alleviating pain and itching that occur as a result of inflammation. It works by numbing the area where the medicine is applied and reduces any unpleasant sensations in or around the anal region. It is for external use only. Use it as directed by your doctor. Do not use it too much or too little as it may increase the side effects or make it less effective. Continue using the medicine as long as the doctor has prescribed. Make sure it does not get to your eyes, mouth, or eyes. In case of accidental contact, wash it off immediately with clean water.It may cause some side effects such as irritation, redness, itchiness, or burning sensation at the side of application. These are usually temporary and resolve themselves in time without any treatment. However, in case they persist or get worse, let your doctor know.Inform the doctor if you have a history of allergic reaction to any of the components of this product. Avoid using Pio Rectal Ointment in case of any systemic infection. Let your doctor also know if you are taking any other medicines to make sure it is safe for you. Pregnant and breastfeeding women should consult their doctors before using this medicine.