Lorbriqua 25mg Tablet
Manufacturer:
Pfizer Ltd
Salt Composition: Lorlatinib (25mg)
Action Class: Tyrosine Kinase Inhibitors (TKIs)
Uses
Treatment of Non-small cell lung cancer
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- SKU: lorbriqua-25mg-tablet-890812
₹40,636
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Product Description
Lorbriqua 25mg Tablet is used to treat adults with unresectable (unremovable), advanced, or recurrent forms of non-small cell lung cancer (NSCLC). It works by inhibiting an enzyme called anaplastic lymphoma kinase (ALK) and is given to patients who have an alteration in this enzyme. Furthermore, Lorbriqua 25mg Tablet is prescribed only to those patients who no longer respond to other ALK inhibitors, such as alectinib or ceritinib. Additionally, it is also effective in treating ALK-positive NSCLC that has spread to the brain.Take this medicine with or without food, but preferably at the same time each day. Depending on the condition and response to the treatment, the doctor may alter the dose or stop the treatment for a short time. Continue taking this medicine for as long as the doctor has prescribed, and do not stop suddenly.Some common side effects of Lorbriqua 25mg Tablet include edema (swelling in arms, legs, hands, and feet), peripheral neuropathy (numbness and tingling feeling in joints, arms, and legs), and cognitive disorders (confusion, forgetfulness, and lack of concentration or attention). It may also cause breathlessness, fatigue, weight gain, joint pain, mood changes, and diarrhea. Consult the doctor if any of these side effects are worrisome or worsen. They may adjust the medicine dose and suggest ways to manage them.Let the doctor know if you have any medical conditions, such as kidney or heart disease, depression, seizures, problems with the heartbeat, or breathing problems. Also, let them know if you have high blood pressure, high levels of cholesterol, or diabetes before starting the treatment with this medicine. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medications may affect the working of this tablet; therefore, tell the doctor about all the other medicines you may be taking before starting the treatment with this medicine.
Key Benefits
In Treatment of Non-small cell lung cancerLorbriqua 25mg Tablet helps shrink the tumor size and restricts the spread of cancer to other parts of the body. This medicine can effectively treat cancer that has spread to the brain because it can cross the blood-brain barrier. This barrier is a network of blood and tissue that prevents infectious bacteria and other harmful substances from entering the brain. The use of Lorbriqua 25mg Tablet helps prevent disease progression and reduce the chances of recurrence over a long period.
Side Effects
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common Side Effects :
Increased triglyceride level in blood
Diarrhea
Cough
Joint pain
Hypercholesterolemia (high cholesterol)
Weight gain
Fatigue
Edema (swelling)
High blood pressure
Peripheral neuropathy (tingling and numbness of feet and hand)
Breathlessness
Mood changes
Common Side Effects :
Increased triglyceride level in blood
Diarrhea
Cough
Joint pain
Hypercholesterolemia (high cholesterol)
Weight gain
Fatigue
Edema (swelling)
High blood pressure
Peripheral neuropathy (tingling and numbness of feet and hand)
Breathlessness
Mood changes
How To Use
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lorbriqua 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How It Works
Lorbriqua 25mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
Alternate Brands
No alternate brands found for this medicine.
Safety Information & Precautions
Alcohol:
It is not known whether it is safe to consume alcohol with Lorbriqua 25mg Tablet. Please consult your doctor.
Pregnancy:
Lorbriqua 25mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding:
Lorbriqua 25mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving:
It is not known whether Lorbriqua 25mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney:
Lorbriqua 25mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Lorbriqua 25mg Tablet may be needed. Please consult your doctor.However, no dose adjustment is recommended for patients with mild or moderate renal impairment.
Liver:
Lorbriqua 25mg Tablet is safe to use in patients with liver disease. No dose adjustment of Lorbriqua 25mg Tablet is recommended.However, recommended dosage regimen has not been established in cases of moderate to severe hepatic impairment.
It is not known whether it is safe to consume alcohol with Lorbriqua 25mg Tablet. Please consult your doctor.
Pregnancy:
Lorbriqua 25mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding:
Lorbriqua 25mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
Driving:
It is not known whether Lorbriqua 25mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney:
Lorbriqua 25mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Lorbriqua 25mg Tablet may be needed. Please consult your doctor.However, no dose adjustment is recommended for patients with mild or moderate renal impairment.
Liver:
Lorbriqua 25mg Tablet is safe to use in patients with liver disease. No dose adjustment of Lorbriqua 25mg Tablet is recommended.However, recommended dosage regimen has not been established in cases of moderate to severe hepatic impairment.
Quick Tips
Take Lorbriqua 25mg Tablet at the same time every day to maintain steady levels in your body.
Swallow the medicine whole with water and do not crush, chew, or split it.
Avoid grapefruit or grapefruit juice, as it can increase side effects.
Let your doctor know if you notice mood changes, confusion, or memory problems.
Keep a regular check on your cholesterol and liver levels as advised during Lorbriqua 25mg Tablet treatment.
Take Lorbriqua 25mg Tablet at the same time every day to maintain steady levels in your body.
Swallow the medicine whole with water and do not crush, chew, or split it.
Avoid grapefruit or grapefruit juice, as it can increase side effects.
Let your doctor know if you notice mood changes, confusion, or memory problems.
Keep a regular check on your cholesterol and liver levels as advised during Lorbriqua 25mg Tablet treatment.
Swallow the medicine whole with water and do not crush, chew, or split it.
Avoid grapefruit or grapefruit juice, as it can increase side effects.
Let your doctor know if you notice mood changes, confusion, or memory problems.
Keep a regular check on your cholesterol and liver levels as advised during Lorbriqua 25mg Tablet treatment.
Take Lorbriqua 25mg Tablet at the same time every day to maintain steady levels in your body.
Swallow the medicine whole with water and do not crush, chew, or split it.
Avoid grapefruit or grapefruit juice, as it can increase side effects.
Let your doctor know if you notice mood changes, confusion, or memory problems.
Keep a regular check on your cholesterol and liver levels as advised during Lorbriqua 25mg Tablet treatment.
Missed Dose
If you miss a dose of Lorbriqua 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.