In Pulmonary arterial hypertension (PAH)Pulmonary arterial hypertension (PAH) is a condition where the blood pressure in the arteries of the lungs becomes abnormally high, causing the heart to work harder and leading to symptoms like breathlessness, fatigue, and chest pain. ENDobloc 5 Tablet is used to treat PAH by helping relax and widen the blood vessels in the lungs. This improves blood flow, lowers lung pressure, and makes it easier to perform daily activities with reduced symptoms, ultimately enhancing exercise capacity and quality of life.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common Side Effects :
Peripheral edema
Nasal congestion (stuffy nose)
Sinus inflammation
Flushing (sense of warmth in the face, ears, neck and trunk)

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. ENDobloc 5 Tablet may be taken with or without food, but it is better to take it at a fixed time.

ENDobloc 5 Tablet is an endothelin receptor blocker. It blocks the action of endothelin (a natural substance) that causes blood vessels to narrow (constrict). This narrowing increases the pressure in the blood vessels of the lungs. ENDobloc 5 Tablet helps relax these blood vessels and increases the supply of blood to the lungs.

Alcohol:
It is not known whether it is safe to consume alcohol with ENDobloc 5 Tablet. Please consult your doctor.

Pregnancy:
ENDobloc 5 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breastfeeding:
Information regarding the use of ENDobloc 5 Tablet during breastfeeding is not available. Please consult your doctor.

Driving:
ENDobloc 5 Tablet may cause dizziness or weakness due to low blood pressure. Do not drive if these symptoms occur.

Kidney:
ENDobloc 5 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of ENDobloc 5 Tablet may be needed. Please consult your doctor.Limited information is available on use of ENDobloc 5 Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate kidney disease.

Liver:
ENDobloc 5 Tablet should be used with caution in patients with liver disease. Dose adjustment of ENDobloc 5 Tablet may be needed. Please consult your doctor.

Your doctor has prescribed ENDobloc 5 Tablet to treat high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries).
It helps improve your quality of life, exercising ability, and delay disease progression.
Your doctor may ask you to get routine blood tests done to check for anemia and to assess the functioning of your liver.
Do not drive or do anything requiring concentration until you know how ENDobloc 5 Tablet affects you.
Notify your doctor if you are pregnant or planning to conceive or breastfeeding.
Females with reproductive potential should use a reliable form of birth control while using and 1 month after stopping ENDobloc 5 Tablet as it is toxic to an unborn baby.
Inform your doctor if you notice weight gain, swelling of your arms and legs, or difficulty breathing.
Your doctor has prescribed ENDobloc 5 Tablet to treat high pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries).
It helps improve your quality of life, exercising ability, and delay disease progression.
Notify your doctor if you are pregnant or planning to conceive or breastfeeding.
Your doctor may ask you to get routine blood tests done to check for anemia and to assess the functioning of your liver.
Do not drive or do anything requiring concentration until you know how ENDobloc 5 Tablet affects you.
Inform your doctor if you notice weight gain, swelling of your arms and legs, or difficulty breathing.
Inform your doctor if you notice yellowing of skin/eye, dark urine, or stomach pain.

If you miss a dose of ENDobloc 5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.